The Slum Boys came into the match as favourites but it was the Sugar Millers who took the lead in the 28th minute when Daniel Otieno capitalised on a defensive lapse to score the opener.
Klinsman Omulanga levelled the score at the 30 minute mark after finishing a beautiful move, but the Patrick Odhiambo-led side was not done.
Enock Agwanda managed to beat the defenders and the goalkeeper to give the Awendo-based side maximum points.
Following Wednesday's result, Sony Sugar has managed to bag four points from Mathare United after the reverse fixture ended in a 1-1 draw.
The Slum Boys are currently fourth in the 18-team log on 35 points.