Why? Because he can no longer play the innocent victim if City are found guilty. He will not be able to claim that he was somehow duped or deceived. In that sense, he's backed himself into a corner, damned by his own flawed logic.
Deep down, he knows full well that the argument put forward by some City fans that the club's players and managers have somehow been operating in a vacuum since 2009, that what happens on the pitch isn't directly related to moves made in boardrooms and financial departments, is pure bullsh*t.
He's even acknowledged himself that City's success would not have been possible without vast amounts of money, and the only relevant question relating to this whole affair is: where has that money come from?
But Guardiola no longer appears interested in the answer. He's already quite deliberately nailed his colours to the City mast. We do indeed know what side he's on, so it doesn't even matter now if it's the winning one.
Guardiola has pointed out that City have great lawyers and they may well beat the case, but the club's reputation has already been tarnished by the charges, and that's what grates with Guardiola. That's why he's so p*ssed off. Despite the show of defiance, he's aware of the impossible position both he and club now find themselves in.
No matter what happens, City will likely hold on to their records and titles, but they'll never regain control of the narrative. As Guardiola said himself, nobody can remove the Aguero moment from City's history. But, by the same rationale, nobody will ever be able to erase that invisible asterisk either.
In that sense, it doesn't matter what else Guardiola wins at the Etihad, he's already lost.