Neymar's Copa hopes were ruined on Wednesday when he suffered an ankle injury early in his team's friendly victory over Qatar.
The Paris-Saint Germain man tangled with Qatar midfielder Assim Madibo and ruptured a ligament in the joint, causing him to be substituted just 21 minutes into the game, which eventually finished 2-0 in Brazil's favour.
His absence from the Copa was confirmed the following day, with the ligament tear expected to keep him on the sidelines for up to six weeks.
He will now return to France, where he will take in the opening match of the Women's World Cup before continuing treatment on his injury at PSG.
"The attacker Willian, of Chelsea, has been called up by the Brazil national team and will play the 2019 Brazil Copa America," the Brazilian Football Confederation confirmed in a statement released on Friday.
"He has been called to replace Neymar, who was dropped from the squad following the friendly against Qatar."
Willian está convocado para a #SeleçãoBrasileira que disputará a Copa América. 🇧🇷⚽— CBF Futebol (@CBF_Futebol) 7 de junio de 2019
Ele ocupará a vaga de Neymar Jr., desconvocado após amistoso contra o Catar.
Saiba mais >> https://t.co/JIXrxTdE6h pic.twitter.com/AKwQkUgT3T
Willian will now have to return to his native Brazil from vacations in Israel, after missing out on Tite's original 23-man call-up.
And, while he was not in the coach's plans initially, the 30-year-old brings a wealth of international experience to the table for his country.
Willian made his debut for Brazil in November 2011 and has gone on to make 65 appearances in the Selecao, scoring eight goals.
He also represented his country in two World Cups, in 2014 on home soil and at Russia 2018, and with Neymar's withdrawal he is the third most experienced player in Tite's squad, behind captain Dani Alves (107 caps) and Thiago Silva (78).