Wilfried Ndidi will represent Leicester City at the ePremier League Invitational, and he will take on Wolverhampton Wanderers forward Diogo Jota in Thursday's last-16 clash.
The competition involves selected players from the 20 Premier League clubs as they test their gaming skills on Fifa 20.
Ndidi is the third African star in the tournament after Crystal Palace's Wilfried Zaha and Newcastle United's Christian Atsu who are playing against Manchester City's Raheem Sterling and Tottenham Hotspur's Moussa Sissoko respectively, on Wednesday.
The week-long event started on Tuesday with 23 goals recorded on day one as Brighton and Hove Albion's Neal Maupay thrashed Aston Villa's John McGinn 6-1 while Bournemouth's Philip Billing defeated Southampton goalkeeper Angus Gunn 4-0.
Ndidi, ranked as one of the top tacklers in the Premier League this season, played a crucial role in Leicester City's rise to third in the league table.
He has made 23 league appearances in this campaign with two goals scored.
