Roberto Mancini’s team are already three points clear at the top after winning all three of their opening group games, putting them three points clear of second-placed Finland.
Unbeaten in 47 World and European qualification matches on home turf, they are 1/3 (1.33) favourites with bet365 to maintain their 100 per cent record with another victory at the Allianz Stadium.
Fiorentina left-back Cristiano Biraghi will play not part after leaving the squad to undergo tests on a knee injury sustained in training last week.
Miralem Pjanic will serve the second match of a two-game suspension for Bosnia, who are also missing Sead Kolasinac and Rade Krunic due to injury.
As well as bedding in exciting young attacking talents such as Nicolo Barella and Moise Kean, Mancini seems to have revived his country’s reputation for defensive excellence over the last few matches.
The Azzurri come into this match on the back of six consecutive clean sheets – their longest such streak since going 10 games without conceding between 1988 and 1990.
They can feel fairly confident of moving one step closer to matching that 10-game sequence considering Robert Prosinecki’s men have not scored a single goal in any of their last four matches on the road and are missing the creativity of Pjanic.
Indeed, odds of 4/5 (1.80) are surely worth backing on Italy keeping a clean sheet on their way to victory for the fifth match in succession, consigning Bosnia-Herzegovina to a third consecutive away defeat without a goal.
All odds correct at time of publish. Please gamble responsibly.