Uruguay and Ghana meet at the Al Janoub stadium on Friday afternoon with both sides looking for a win to qualify for the knockout stages from Group H.
This is something of a grudge match following their controversial quarter-final meeting at the 2010 World Cup in South Africa which La Celeste won, meaning the Black Stars will be out for revenge.
Ghana vs Uruguay latest odds
They are yet to score a goal in the tournament, but Uruguay are strong favourites to claim a win with bet3565 offering them at 8/11 (17.3).
Ghana are the lowest ranked team in the tournament but have scored five goals so far and are priced at 15/4 (4.75) with the draw at 14/5 (3.80).
Ghana vs Uruguay first goal scorer odds
Luis Suarez's infamous handball in the meeting between these nations 12 years ago made him public enemy number one in Ghana.
The former Liverpool striker is priced at 9/2 (5.50) to further antagonise his African opponents by opening the scoring, while Darwin Nunez and Edinson Cavani are both priced at 11/2 (6.50).
Real Madrid star Fede Valverde is available at 9/1 (10.00) the same price as Ghana's Andre Ayew.
Ghana vs Uruguay preview
Given the context of the group this is a winner-takes-all encounter, with Ghana definitely through if they win and Uruguay needing South Korea not to beat Portugal.
The pressure is certainly on the South Americans who would have expected to qualify from the group and they are likely to feel the nerves the longer the game goes on goalless.
Ghana's matches so far have been open and exciting, and that should play into Uruguay's hands given their superior squad.
La Celeste should finally be able to showcase their firepower and backing them to get among the goals against a side that has conceded five times so far should appeal.
Ghana vs Uruguay tips and predictions
Uruguay to score over 1.5 goals looks a strong option for this game at 5/6 (1.83) with South Korea and Portugal both managing to net at least twice against the west Africans.
Odds correct at the time of writing. Please gamble responsibly.
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