The build up to the Wembley clash has been dominated by some big-name absentees for Gareth Southgate to deal with including Harry Kane, Dele Alli and Jordan Henderson.
The Three Lions are rated as 13/5 (3.60) shots by Betfair Sportsbook, but the online firm have a fantastic enhanced price available on any punters who want to back the hosts at much bigger odds.
Simply open an account through the link provided and get 33/1 (34.0) on Southgate's side coming out on top. £1 max bet. Winnings paid as free bets. T&Cs apply.
Germany are Evens (2.0) to pick up a victor,y but Joachim Low has hinted at naming something of an experimental side and using the opportunity to examine how his squad fare ahead of next summer's tournament in Russia.
That could certainly give hope to England backers who can envisage the home team extending their winning run to five matches having eased through the final rounds of World Cup qualification.
There hasn't been a draw between these two teams in any of the previous nine head-to-head meetings, but that is available at 12/5 (3.40) with Betfair at the time of writing.
While Friday’s visitors did win the previous encounter by a 1-0 score line, a late Eric Dier winner gave England a 3-2 victory in Berlin last March. The Tottenham man is expected to captain his country here and Jamie Vardy, also on the scoresheet in the Olympiastadion that night, could start up front.
This encounter as well as the meeting with Brazil is one of the final opportunities for players on the fringes of the national set up to prove themselves to Southgate and as such, motivation shouldn’t be an issue.
With neither side likely to be at their best, the 33/1 (34.0) could well prove a popular option for punters who want to take a chance on England at a big price in a game that is always keenly contested.
They will remain outsiders of course, but the double figure quote is certainly an attractive option for anyone who doesn't already have an account and wants to cheer on a big price selection in Friday's clash.