Usually Manchester United hosting a top four rival would look like an obvious opportunity to oppose goals.
That might not be the case on Monday evening though, with Jose Mourinho's side coming under increasing pressure on and off the field. Some improvement is to be expected, but Spurs have already scored five goals this term and should be confident of making at least one breakthrough.
David De Gea has now conceded 10 times from the last 14 shots on target he's faced for club and country since the start of the World Cup.
Over 2.5 goals has been popular with punters and is now 10/11 (1.91) with bet365 while both teams to score is a 4/6 (1.67) shot and those prices appeal more so than usual when it comes to matches at this venue.
The fact that United's defence was so unconvincing in conceding three times against Brighton at the Amex last time out could mean the scorer markets are of interest and there are plenty of options to choose from.
Paul Pogba is 10/3 (4.33) to score anytime and that might appeal to some punters given that the midfielder has been on penalty duties during the first part of the campaign.
The man to back though, is Harry Kane. It's not the most original of selections - he's 11/10 (2.10) to score - but the 25-year-old's record against elite Premier League opposition is very impressive, especially with United looking tough to trust at the back.
Those searching for a bigger price can get 15/4 (4.75) to score first, something the Spurs striker did 14 times last season, tied with Jamie Vardy for the most of any player in the division.
Kane has 18 goals - two more than Lukaku - against 'big six' opposition in the top flight. That's despite playing 2008 minutes fewer and taking 31 fewer shots in games against the biggest clubs in the division.
Having broken the so-called August hoodoo in his previous match, Kane is well worth backing at 11/10 (2.10) to make his mark at Old Trafford, especially with Mourinho’s men looking uncharacteristically soft centred.