Both sides from the capital of Spain have endured difficult starts to the season, although it is a measure of how far Diego Simeone's men have progressed that to be level on points with Real Madrid after eleven matches can still be deemed disappointing.
Atleti's woes this term have mainly come in Europe where are they on the verge of suffering an unexpected elimination from the Champions League, although domestically they have been underwhelming at times despite remaining unbeaten.
Los Blancos, for their part, begin the weekend eight points behind leaders Barcelona, and their inability to find a clinical edge in front of goal has cost them a number of vital points already.
Realistically, Zinedine Zidane will know that only a win will do for his side, who cannot afford to slip further behind their Catalan rivals even if there is a long way to go yet in the season.
Therefore, the stage is nicely set for a Madrid derby where both sides will be desperate for the points, and dabblebet customers can watch and bet on this fixture via desktop, mobile and tablet. Your account must be funded or active in order to see the action live.
Central to both teams' perceived problems this season has been a relative lack of firepower, and despite each boasting numerous talented creative players, neither side have scored as many goals as they should have; indeed, there is a strong argument to be made that backing a low-scoring game is the smart move here and under 2.5 goals is priced at a potentially appealing 5/6 (1.83).
This bet has paid out in 12 of Los Rojiblancos' last 14 matches and in each of their last eight games in all competitions, although for Real Madrid, four of their five away league matches this term have seen three goals or more.
Perhaps, therefore, a wiser bet is backing 2-3 goals in the game at evens (2.00), with this selection paying out in each of the last five meetings between the sides - including all four of their encounters last season.