Arsenal's 22-game unbeaten run came to an end against Southampton last weekend and they will be looking to get back on track with a win over Burnley this weekend.
The Gunners have lost two consecutive games, with a north London derby loss against Spurs on Wednesday night following defeat to Saints in the league.
Unai Emery's men have scored a total of 37 goals this season, which is only bettered by Manchester City's incredible tally of 48, but have suffered defensively in recent games due to a number of injuries at the back.
Rob Holding will miss the rest of the season after suffering a cruciate ligament knee injury.
Danny Welbeck is ruled out with a broken ankle following his shocking injury against Sporting CP, and Henrikh Mkhitaryan has now sustained an ankle injury that keeps him out until the turn of the year.
Hector Bellerin has been ruled out for at least another two weeks with a calf problem, with Sead Kolasinac and Shkodran Mustafi likely to be unavailable again after thigh and hamstring problems, respectively.
Emile Smith Rowe is still recovering from injury as well, although Dinos Mavropanos is back in light training and expected to be in contention in the coming weeks.
Arsenal have no suspended players for this match.
Possible Arsenal Starting Line-Up
Emery's defensive headache means that Stephan Lichtsteiner should start at right-back in place of the injured Bellerin.
Mesut Ozil is fit although he wasn't picked for the defeat against Spurs in the Carabao Cup due to 'tactical reasons' while Alexandre Lacazette could return up front.
Swiss midfielder Granit Xhaka has played at centre-back in recent games and is likely to continue in that role for this one.
Burnley Team News
Burnley are without Aaron Lennon after the winger had a knee operation, but Johann Berg Gudmundsson and Robbie Brady could be fit after their respective injury problems.
Sean Dyche fielded an unfamiliar 3-4-3 formation in the recent game against Spurs, although his side have failed to win on the road since victory over Cardiff in September.
TV Coverage & Kick-Off Time
Kick-off is 12:30pm GMT (7:30am ET) on Saturday, and the game will be broadcast live on Sky Sports in the United Kingdom. It will be shown on NBCSN in the United States, and on various channels around the world.
Best Opta Match Facts
- Arsenal are unbeaten in each of their last 10 matches in all competitions against Burnley (W9 D1), conceding just four goals in the process and never more than once in a game.
- Burnley have lost all four of their Premier League matches against Arsenal at the Emirates by an aggregate score of 13-2.
- Arsenal are looking to avoid consecutive Premier League defeats for the first time since the opening two games of the season.
- Burnley boss Sean Dyche has lost all seven of his matches against Arsenal as a manager, with his teams conceding 15 goals and scoring just twice.
- Arsenal’s Pierre-Emerick Aubameyang has been directly involved in 17 goals in his 16 Premier League home games (12 goals, 5 assists), including two goals and an assist against Burnley in this fixture last season.