The defending champions were in imperious form as they claimed a crushing 5-0 victory against Cardiff City in the Welsh capital last weekend whilst Brighton have failed to win any of their last 16 Premier League matches away from home.
It is no real surprise, then, that SportPesa make Manchester City their 1/15 (1.07) favourites to pick up all three points this weekend.
Brighton are chalked up as a 37/1 (38.0) chance to claim their first Premier League away win in more than 10 months when they take on Pep Guardiola’s charges.
With a crucial Champions League trip to Hoffenheim looming large, Guardiola is expected to shuffle his pack, but the former Barcelona and Bayern Munich boss has plenty of first class options at his disposal.
Sergio Aguero, Fernandinho, Fabian Delph and Bernardo Silva were not in the squad for the EFL Cup tie against Oxford United on Tuesday night, but Riyad Mahrez, David Silva and Gabriel Jesus all started that match and will harbour hopes of playing their part against the Seagulls.
Brighton will hope that Pascal Gross is fit to make the trip to Manchester after missing out against both Southampton and Spurs this month, while Florin Andone could make his debut for the Seagulls after being named as an unused substitute last time out.
City cruised to a 3-0 win in their last Premier League home match and after scoring eight goals without reply in their last two matches, any negative thoughts in the aftermath of a shock Champions League defeat against Lyon have surely been banished.
Guardiola will be desperate to see his side start this match well so that he can rest and rotate key men in the latter stages ahead of Tuesday’s trip to Hoffenheim.
The Seagulls may struggle to keep pace and SportPesa’s 11/10 (2.10) quote for Manchester City to score more than one first half goal could well provide punters with a path to profit on Saturday afternoon.