Having played away from home in the previous round, the Buccaneers will enjoy the home ground advantage in the Last 8 with a meeting against Polokwane City.
Kgoloko Thobejane's men upset the odds to defeat Cape Town City in Polokwane. This was City's third successive defeat, and questions will be asked about their sudden loss of form under Benni McCarthy.
The PSL will announced dates, venues and kick-off times for the four matches in due course.
Full draw below:
Orlando Pirates v Polokwane City
Chippa United v Kaizer Chiefs
Platinum Stars v Bloemfontein Celtic
Bidvest Wits v Baroka FC