Barcelona have one foot in the semi finals of the Champions League already and only an enormous upset by AS Roma at the Stadio Olimpico would prevent the inevitable.
The Blaugrana's 4-1 win over Roma at the Camp Nou last week affords them a comfortable margin for error and an early goal for Ernesto Valverde's men would surely put the tie beyond doubt.
Latest odds
Barca have a poor record on the road in Europe, having won just two of their last eight games away from home in the Champions League, but are still available at 8/13 (1.61).
Indeed, their last three away games in the Champions League have ended in draws and bet365 price a repeat at 7/2 (4.50).
Getty ImagesRoma are offered at the same price, and may be good value as they are unbeaten at the Stadio Olimpico in the competition this term, keeping four clean sheets in four games.
Team news
Sergio Busquets, Jordi Alba, Andres Iniesta and Samuel Umtiti were rotated in the weekend win over Leganes and are all likely to start for a Barca side who have no major injury concerns.
For Roma, Radja Nainggolan missed the first leg but is available for selection after featuring in Saturday's loss to Fiorentina.
Few goals in Rome
While the hosts know they need goals to have any hope of progressing, realistically they will be aware of the fact that the task is practically impossible.
This second leg is not quite a dead rubber, although it will perhaps feel like both sides are going through the motions and acutely aware of the likely outcome.
To this end, backing a low-scoring game makes sense and the respective results from both sides in this season's competition reinforce this idea.
Tips and predictions
Under 2.5 goals is priced at a healthy looking 7/5 (2.40). This bet has paid out in all four of Barca's away games in the Champions League this season, while also proving the correct selection in three of Roma's four home matches.
Under 2.5 goals at 7/5 (2.40) with bet365 for a 1.5pt stake