Los Blancos were out at 9/2 (5.50) before kick-off, but a brace from Cristiano Ronaldo – including a sumptuous bicycle kick – means that the current champions are now backed in to 11/4 (3.75).
Few could have expected Real to hand out the kind of punishment they did to the Serie A Leaders, especially away from home, but Zinedine Zidane’s men showed no mercy to all-but secure their passage into the semi-finals for the eighth consecutive season.
Barca in the running
Juventus, meanwhile, have been pushed out to 250/1 (251.0) as the elusive Champions League title slips further out of Gianluigi Buffon's grasp.
Real’s El Clasico rivals Barcelona have been cut to 5/2 (3.50) from 11/4 (3.75) without playing, but that could shorten even more if they claim a first leg victory over 66/1 (67.0) Roma on Wednesday.
A trip to the Camp Nou will likely be too much to handle for a Roma side that has won just one of their last 14 away matches in the tournament – a run that includes a 6-1 thrashing at Barca.
Bayern's time?
Bayern Munich were also slightly shortened to 3/1 (4.0) after their 2-1 win at Sevilla, which saw them come from behind to complete the victory and also grab two potentially valuable away goals.
Indeed, their 150/1 (151.0) Spanish opponents have won just three of their last 15 matches on the road, although they did shock Manchester United 2-1 at Old Trafford in the last 16.
Liverpool and Manchester City’s odds have not changed ahead of their showdown at Anfield on Wednesday night, with the Reds out at 12/1 (13.0) whilst the Premier League champions-elect can be found at 10/3 (4.33).
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