The 24-year-old, who spent last season on loan at Charlton Athletic, hasn't played in 2016-17, with Arsene Wenger cagey over the reason for his absence.
The Gunners boss revealed back in December that he couldn't explain what was wrong with the Frenchman, and that the details of an apparent injury were "confidential".
His agent has been similarly guarded over Sanogo's continued absence although he is now finally back on the pitch as he prepares to take on Spurs in the Under-23 clash.
And fans of the north Londoners were quick to jump on the news, with many reacting to Sanogo's name being on the team-sheet, despite the presence of the likes of Mathieu Debuchy and Carl Jenkinson.
@Arsenal buzzing for wild card Yaya to score a hatty vs Bayern.— TheFooTypster (@TheFooTypster) March 3, 2017
@Arsenal I know we hate Tottenham but not enough to destroy 11 kids careers by making them face Sanogo at such a young age— Saswat. thats me. (@Exquisitemate) March 3, 2017
@Arsenal Sanogo lives!— Karabo Sekgororoane (@KaraboSkay) March 3, 2017
Sanogo has made a total of 11 Premier League appearances for Arsenal over his career, although hasn't featured for the Gunners in the league since a 2-1 defeat to Swansea in November 2014.