Manager Thomas Tuchel had opted to shake up his starting XI for this final group game, making five changes from the side that was held to a stalemate by Ghana. With Reece James sidelined due to a hamstring injury, Jarell Quansah stepped in at right-back, while Marcus Rashford and Bukayo Saka were restored to the wings in place of Anthony Gordon and Noni Madueke.
The tactical shift saw Morgan Rogers join the midfield in a more attack-minded setup, but the Three Lions found it difficult to find their flow early on. Rashford forced a smart save from Mosquera in the seventh minute, but Panama remained a threat on the counter-attack, forcing Jordan Pickford into a finger-tip save from Jose Rodriguez midway through the first half.