This latest surgical intervention adds to a bleak fitness record for the defender over recent seasons. Before the international break, a separate knock ruled him out of a 3-0 loss to Brentford, which subsequently cost him a spot in Thomas Tuchel's England squad.
James had initially made a brief return to the training pitch ahead of the Bournemouth clash, raising hopes of an imminent comeback. However, manager Xabi Alonso revealed that the defender immediately experienced discomfort.
"He felt something, but after we did the tests later in the afternoon," Alonso explained. "He had some little issues on the knee, so we need to check how long it will be. We will assess it week by week."