His imminent exit was seen as an extra incentive for the players to secure a Europa League crown to send the 68-year-old off on a high.
But, after drawing 1-1 at home with 10-man Atletico Madrid, Arsenal lost 1-0 in Spain on Thursday as familiar foe Diego Costa scored the decisive goal.
And Wenger acknowledged it is a sad ending for him, with his last game at Arsenal set to be against Huddersfield Town rather than in a European final.
"It's very sad, very, very, very sad," said Wenger. "I'm very sad to leave the club with that exit.
"It takes some time to recover from that, after I will see what I do with myself in the future. I have no plans at the moment.
"I am like the team; very sad and very disappointed, even very frustrated, as well, because when you go out of a competition and you had the performances in the 180 minutes that we had, it is very difficult to take.
"We missed something in the final third. You look at the number of chances we created in the two games, the least you can say is we can be very frustrated.
"Congratulations to Atletico and good luck in the final. The winner of tonight's game is the clear favourite to win the competition.
"Overall they are a clever side who defend very well. [Diego] Godin tonight saved five, six balls on crosses, absolutely, in amazing positions. They have great defenders."