Sean Dyche's side pulled themselves out of the bottom three with a vital victory against Brighton last weekend and the Clarets will hope that that victory gives them a platform on which to build.
Spurs have made their best-ever start to a Premier League season and will be in buoyant mood after securing a place in the knockout stages of the Champions League with a hard-fought 1-1 draw against Barcelona on Tuesday night. The hosts are 888Sport's 1/6 (1.17) favourites to continue their pursuit of Liverpool and Manchester City at the top of the table with a win at Wembley.
Burnley have won just one of their eight Premier League matches away from Turf Moor this term and the Clarets are chalked up as a 17/1 (18.0) chance with 888Sport to stun Spurs.
The same firm go 13/2 (7.50) that the match ends all square - Spurs are the only Premier League team yet to draw a league match thus far this term.
Harry Kane and Christian Eriksen were named as substitutes against Leicester City last weekend and, despite an energy-sapping night in Barcelona on Tuesday, both men are expected to start this one.
Nick Pope remains out for Burnley, but Dyche has an otherwise fully fit squad from which to choose ahead of the trip to Wembley.
Mauricio Pochettino's team have scored three goals in both of their last two Premier League matches at Wembley and 888Sport go 3/4 (1.75) that Tottenham score three or more goals on Saturday.
Chink of light for the Clarets?
Burnley have drawn a blank in three of their last four league matches away from Turf Moor and 888Sport go 3/4 (1.75) that Spurs shut out Dyche's side.
However, Pochettino's men have managed just one clean sheet in their last league matches at Wembley this term and 888Sport go 11/10 (2.10) that there are goals at both ends.
Only Fulham have conceded more goals than the Clarets in the Premier League this season and Dyche's team may attempt to stifle Spurs.
Pochettino's men could be forgiven for lacking their usual sharpness on the back of their exertions in European competition in midweek and value could lie in backing a low-scoring clash at Wembley this weekend.
888Sport offer 19/10 (2.90) that there are fewer than three goals scored - that particular play would have landed in six of Spurs' last 10 matches in this competition, as well as in three of the Clarets' last five fixtures.