Having failed to come out on top against this opposition since a 2-1 victory back in November 2012, Mauricio Pochettino's men are available at 5/4 (2.25) with dabblebet to secure a long-awaited win five years later.
However, the Reds have won just once in their last five matches in the league, and are 11/5 (3.20) outsiders to maintain their strong record by emerging victorious here.
Three of the last four league meetings between the sides have resulted in draws, and you can get odds of 5/2 (3.50) on them cancelling each other out once again in this one.
Despite Jurgen Klopp's reputation for free-flowing football, this particular fixture has become far less high-scoring since he made his English debut in a 0-0 draw at White Hart Lane two years ago.
Having averaged just under three goals a game in the Premier League era prior to the German's arrival, the four encounters since he took over have produced just six in total - almost exactly half of that average.
This is most easily explained by the similar tactics employed by both Klopp and Pochettino, with their intense pressing games serving to effectively cancel each other out in head-to-head clashes.
Considering Spurs have struck just three times in four league games at their temporary Wembley home so far and their guests have only scored five goals in their last five league games, another tight encounter appears likely on Sunday.
With this in mind, odds of 23/20 (2.15) offer solid value on under 2.5 goals being scored for the fifth consecutive league encounter between these sides, as well as Tottenham's fourth consecutive home league game and Liverpool fourth league fixture in five.