The three players spent last season on loan at the Port Elizabeth-based outfit but Malepe had been there for more than just a season, after being allowed to go and get game time elsewhere following his promotion to the Bucs first team.
Thopola, Malepe and Maphangule will now return to the parent club, Pirates, who will then decide whether to keep them, loan them out for another season or release them from their contracts.
"Diamond Thopola, Tercious Malepe and Meshack Maphangule who were all loaned from Orlando Pirates Football Club. Their loan contracts expired and will not be returning for the 2020/21 season," said Chippa in a statement.
The trio follows Thabo Rakhale, Boikanyo Komane and Gerald Modisane through the exit door after they were also released upon the expiry of their contracts with Chippa United.
"Thabo Rakhale, Boikanyo Komane and Gerald Modisane their contracts expired. The club will not be renewing their contracts," the statement added.
Furthermore, the Chilli Boys confirmed parting ways with no less than seven other players in Ruzaigh Gamildien, Lehlogonolo Masalesa, Kelvin Moyo, Elvis Moyo, Phetso Maphanga, Ryan Baartman and William Twala.
According to the club, the contracts of the abovementioned players were terminated by mutual agreements.
Lastly, Athini Jobodwana will be loaned out alongside Ronaldo Maarman for the upcoming campaign.
Jobodwana, 26, only joined Chippa United from Steenberg United during the January transfer window and made nine appearances across all competitions.
"Following meetings with the players, mutual agreements were reached to terminate the contracts of Ruzaigh Gamildien, Lehlohonolo Masalesa, Kelvin Moyo, Elvis Moyo, Phetso Maphanga, Ryan Baartman and William Twala," it added.
"Athini Jodwana, who joined the club in January, will be loaned out for the 2020/21 season alongside with Ronaldo Maarman."
The latest developments are seen as Lehlohonolo Seema's attempts to work with players of his choice as he starts working on a new project following his arrival from Bloemfontein Celtic a few weeks ago.
The Chilli Boys will be expected to replace the outgoing players with new faces in preparation for the 2020-21 season which gets underway in October.