Spurs are not in action until Monday night and Antonio Conte's charges will close to within two points of Mauricio Pochettino's team by taking all three points in south Wales.
Chelsea are chalked up as a 1/2 (1.50) chance with dabblebet to do just that, while the odds compilers offer 16/5 (4.20) that the Blues are forced to settle for a share of the spoils on this occasion.
The Swans have been beaten in just two of their last 10 league matches on home soil and can be backed at 6/1 (7.0) to win this weekend.
Marcos Alonso completes his three match ban against the Swans and the Spanish star will again be a big miss for the Blues. David Luiz and Danny Drinkwater remain out.
Renato Sanches, Leroy Fer and Wilfried Bony are long-term absentees for the Swans, with all three men expected to miss the remainder of the campaign.
Carlos Carvalhal will be hopeful that Luciano Narsingh is passed fit whilst Sam Clucas could start after coming off the bench last weekend, but Federico Fernandez is rated as doubtful.
There have been at least three goals scored in six of the last seven Premier League matches that Chelsea have contested away from Stamford Bridge and dabblebet go even money (2.0) that the trend continues in this clash.
The Blues have failed to find the net in just one of those seven matches, while Swansea have scored in five successive Premier League matches at Liberty Stadium.
Indeed, dabblebet offer a tempting 6/5 (2.20) that both teams are on target on this occasion.
Swansea have not won any of their last six fixtures in all competitions and Chelsea can maintain their quest for Champions League qualification with a vital victory.
Conte's side will come into this match in confident mood and the 5/6 (1.83) quote for the Blues to win a match featuring at least two goals could represent good value for punters.