Zinedine Zidane rested some key players in Madrid's 2-1 victory at Getafe with Luka Modric and Isco starting the game on the bench, although the Spain international was called upon midway through the second half with the score at 1-1 and his marvelous assist for Cristiano Ronaldo's late winner confirmed the growing feeling that Isco is currently Los Blancos' most in-form player.
He and Modric will likely come back into the starting lineup for Tuesday's clash, with Ronaldo and Karim Benzema, who both scored their first league goals of the season in Getafe, likely to be the forward duo for the European champions.
Mauricio Pochettino meanwhile played a full strength team as Spurs beat Bournemouth 1-0 at Wembley, yet their most in-form player Harry Kane was not the matchwinner, as the striker drew a blank for the first time in six matches.
Nine goals in his previous five games for club and country has underlined Kane's status as Spurs' key player, although the side were still able to find a winner in Christian Eriksen on Saturday when the England striker was not able to score.
There have been rumours of a move to a the Bernabeu for Kane and a big performance in Madrid would surely reignite those suggestions; Spurs' number ten has scored five of the team's six Champions League goals and dabblebet offer him at 5/4 (2.25) to score at anytime. The only other player for the Premier League side to have scored in Europe this term is Son-Heung Min, who is priced at 11/4 (3.75) , while weekend hero Eriksen can be backed at 7/2 (4.50) .
For the hosts, of course Ronaldo leads the way and the top scorer in the history of the competition is understandably priced at 4/11 (1.44) to score at anytime time and more appealingly offered at 8/5 (2.60) to score two or more, or alternatively can be grabbed at the same price to break the deadlock.
Karim Benzema is just behind him in the betting at 3/4 (1.75) to score and add to his 51 goals in 96 Champions League appearances; indeed, the Frenchman looked extremely sharp at Getafem producing some superb touches as well as taking his goal expertly and will be keen to continue his comeback from injury with another strike.
Elsewhere, Isco is priced at 11/8 (2.38) and the Spain international has scored seven times for club and country this season, while Marco Asensio can backed at 8/5 (2.80) to score his first goal since the 27th August.