Pep Guardiola's side is littered with creative talent and Kevin De Bruyne was looking to defend his crown as the English top flight's assist king.
He faced stiff competition from team-mates David Silva and Leroy Sane, though, as well as the likes of Riyad Mahrez, Willian, Mesut Ozil, Dele Alli and Mohamed Salah.
Paul Pogba was also in the race, but star turns at the Etihad Stadium have edged clear of a Manchester United rival once again at the top of the charts.
Goal brings you the final Premier League assists ranking...
Premier League 2017-18 most assists
The title appeared set to be shared after De Bruyne's City team-mate Sane joined him on 15 assists after a hat-trick of assists in the 3-1 win over Brighton.
However, in the fourth minute of stoppage time in the final game of the season at Southampton, De Bruyne set up Gabriel Jesus for the winner to successfully defend his playmaker crown.
The top four is rounded off by City players, too, with Raheem Sterling and Silva on 11 assists.
Outside of the City quartet, Pogba, Christian Eriksen, Mahrez, Salah and Alli are the only other players to reach double figures for assists this season.
Henrikh Mkhitaryan also figures highly in the rankings with nine assists.
Pascal Gross, Aaron Ramsey, Johann Berg Gudmundsson and Ozil are next in line.
Most assists in the Premier League:
*Correct as of May 13, 2018
|1||Kevin De Bruyne||Manchester City||16|
|2||Leroy Sane||Manchester City||15|
|=3||David Silva||Manchester City||11|
|=3||Raheem Sterling||Manchester City||11|
|=5||Paul Pogba||Manchester United||10|
|=5||Riyad Mahrez||Leicester City||10|
|=11||Pascal Gross||Brighton & Hove Albion||8|
|=11||Johann Berg Gudmundsson||Burnley||8|
|=15||Marc Albrighton||Leicester City||7|
|=15||Romelu Lukaku||Manchester United||7|
|=15||Chris Brunt||West Brom||7|
|=15||Aaron Cresswell||West Ham||7|
|=15||Xherdan Shaqiri||Stoke City||7|
|=15||Andros Townsend||Crystal Palace||7|
|=26||Alexis Sanchez||Manchester United||6|
|=26||Joe Allen||Stoke City||6|
|=26||Sergio Aguero||Manchester City||6|
|=26||Kyle Walker||Manchester City||6|
|=26||Manuel Lanzini||West Ham||6|
|=26||Marko Arnautovic||West Ham||6|
Who finished on top in 2016-17?
De Bruyne had the most assists in the Premier League last season, racking up 18 for Manchester City.
De Bruyne's closest rival was Tottenham playmaker Eriksen, who amassed an impressive 15 assists as Spurs finished second in the top flight.
Gylfi Sigurdsson, Cesc Fabregas and Alexis Sanchez rounded out the top five.
The past five winners prior to De Bruyne were Ozil, Fabregas, Steven Gerrard, Juan Mata and Silva.