It was Spurs' third straight win in the Premier League, and marked 11 games unbeaten since folding to Manchester City shortly before Christmas.
In doing so, the manager enters an elite group of bosses who have managed the mark with such speed.
Only six managers reached the milestone in fewer games. Jose Mourinho leads the way, having won 100 of his first 142 matches, ahead of Alex Ferguson, who needed 162 contests to get a century of victories.
100 - Mauricio Pochettino has reached 100 Premier League wins as a manager in 197 games – the joint-6th quickest alongside Kenny Dalglish. Only Jose Mourinho (142), Alex Ferguson (162), Arsene Wenger (179), Rafa Benitez (181) & Claudio Ranieri (187) reached it in fewer games. Ton pic.twitter.com/MqKt3yKHXE — OptaJoe (@OptaJoe) March 3, 2018
Arsenal boss Arsene Wenger is next on the list (179 matches), ahead of Rafa Benitez (181) and Claudio Ranieri (187).