With just three points to their name themselves, the Partenopei are on offer at 2/5 (1.40) to secure the win they need in order to maintain their own slim chances of progression.
None of the hosts’ last nine fixtures in this competition have resulted in draws, but you can get odds of 4/1 (5.00) on them being held to a stalemate in this one.
Clear favourites to qualify alongside Manchester City when the group was drawn, Maurizio Sarri’s team is now up against it to make it through to the next round.
The Italians must now win by at least that scoreline in this return clash in order to take the lead in the head-to-head stakes, with a very winnable trip to Feyenoord coming up in their final clash while their opponents host Manchester City.
This is certainly achievable for a team that has won 12 and lost just one of their last 15 games on home turf, with the visitors having lost five of the previous six away matches in the Champions League.
However, having failed to keep a clean sheet in seven matches in this competition, odds of 13/8 (2.63) look good on Napoli coming out on top despite conceding for the second successive Champions League home game.