With Romelu Lukaku unlikely to start after returning late from holiday following the World Cup, Sanchez looks a strong candidate to open the scoring at 4/1 (5.00) with SportPesa.
In contrast, Lukaku’s 20/21 (1.95) price seems slightly short considering he is expected to start the match on the bench and is unlikely to be at full fitness anyway.
The Belgian’s absence could also offer an opportunity for Marcus Rashford to demonstrate his own qualities in front of goal, with the 20-year-old available at 8/5 (2.60) to open his account for the campaign at the first time of asking.
Also facing the prospect of a starting line-up without their star striker thanks to Jamie Vardy’s World Cup exertions, the Foxes will be hoping Kelechi Iheanacho can replicate his prolific pre-season form at Old Trafford.
Former City man to strike?
The former Manchester City striker struck four times in three friendly matches over the summer, and can be backed at 12/1 (13.00) to keep that streak going with the opener, or 9/2 (5.50) to score anytime.
With 57 goals to his name over the last three Premier League seasons, Vardy may still be his team’s best prospect attacking even as a substitute at 3/1 (4.00) odds.
Having joined Claude Puel’s team for £20 million after hitting 14 goals from midfield in the Championship last season, James Maddison is on offer at 5/1 (6.00) to make a memorable first impression with a debut goal here.