Manchester City will be looking to get their Champions League campaign off to a winning start when they welcome Lyon to the Etihad Stadium on Wednesday.
Having proved so dominant in the Premier League, Pep Guardiola's men were disappointingly knocked out of last season's competition by Liverpool in the quarter-finals.
With the former Barcelona boss determined to reach his first Champions League final since 2011, his side are overwhelming 2/11 (1.18) favourites with bet365 to take the first step by collecting three points here.
Les Gones have won just three of their last 13 fixtures in this competition, and are 16/1 (17.00) long shots to pull off a shock victory in this one.
None of the hosts' last 12 European matches have resulted in draws, but there are odds of 15/2 (8.50) available on them being held to a stalemate on this occasion.
Benjamin Mendy and Sergio Aguero are both doubts due to injury, while Claudio Bravo and Kevin De Bruyne remain long-term absentees.
Fernando Marcal is unlikely to feature due to a calf injury, with Amine Gouiri also sidelined after rupturing his cruciate ligaments.
After missing out on Champions League qualification last season, Bruno Genesio's team will be keen to make up for lost time on their return to the competition.
Having found the net in all but six of their last 52 fixtures in all competitions, the visitors will certainly fancy their chances of getting on target against a home team that has kept just four clean sheets in 17 Champions League games.
Nevertheless, City's superior quality is likely to prove telling, with odds of 6/5 (2.20) well worth backing on Lyon coming away empty-handed despite getting on the scoresheet.
Odds correct at the time of writing. Please gamble responsibly.