However, Pep Guardiola's men have found the net in all 20 of their home matches so far this campaign, scoring 75 goals in the process.
Indeed, Sergio Aguero alone will take some stopping after scoring six times in his last five appearances, making him a relatively narrow 16/5 (4.20) shot with William Hill to open the scoring.
Boasting 12 goals to his name in 16 games versus the Blues, anytime odds of 17/20 (1.85) actually look fairly generous on him coming up with the goods against a visiting defence that conceded four to Bournemouth in their previous away match.
The Argentine's strong recent form has been particularly important considering second top-scorer Raheem Sterling has only been on target twice in his last 13 games, making him a longer 29/20 (2.45) shot to strike here.
Similarly, Leroy Sane has scored only twice in 11 league games, and is priced at 8/5 (2.60) to get on the scoresheet here.
At the other end of the pitch, Gonzalo Higuain will be hoping to build on an encouraging performance against Huddersfield that saw him open his Premier League account with two goals.
However, that was just the second match in 15 in which the on-loan striker has been on target going back to his time at AC Milan, and he is available at long 15/2 (8.50) and 21/10 (3.10) anytime odds.
Top scorer Eden Hazard ended a five-match barren streak to also score twice against Huddersfield, and is priced at those same 21/10 (3.10) odds to add to that at the home of the champions.
Hazard will be particularly keen for Higuain to hit the ground running given how much he has shouldered the goal-scoring burden this season, with second top scorer Pedro a lengthy 16/5 (4.20) anytime shot after scoring just once in 10 games.