City chalked up an astonishing 16th consecutive league win as they cruised to a supremely comfortable 4-1 victory against Tottenham Hotspur last weekend and the men from Manchester are showing no signs of slowing up ahead of their clash against the Cherries, having come through a nerve-shredding penalty shoot-out victory against Leicester City in the League Cup in midweek.
Guardiola's charges, who have dropped just two points in 18 Premier League matches this season and are yet to be beaten in the top tier, are chalked up at just 11/100 (1.11) with Betsafe to maintain momentum with a win.
Howe's men came agonisingly close to taking a share of the spoils when these teams met at Vitality Stadium earlier in the season; Raheem Sterling struck deep in stoppage time to break Bournemouth hearts and Betsafe offer 25/1 (26.0) that the visitors take their revenge by inflicting a first domestic defeat of the season on City, while the same firm go 21/2 (11.50) that this match ends all square.
Hosts hot favourites to maintain magnificent form
The Cherries cannot come into this fixture in confident mood, for they have failed to win any of their last seven fixtures. Bournemouth were battered 4-0 by Liverpool before crashing out of the League Cup against Chelsea in midweek and it would take a remarkable reversal in fortunes for Howe's men to take anything from the daunting trip to Etihad Stadium.
Indeed, the enormity of the task facing the visitors is reflected by the 7/25 (1.28) quote on offer from Betsafe for Manchester City to lead at both half time and full time, while the same firm go 21/25 (1.84) that the men from Manchester win by at least three clear goals.
That particular play may well prove popular given the way that the Cherries crumbled in the face of Liverpool's impressive attacking impetus last weekend; City are even more potent in the final third of the pitch, having already notched an astonishing 56 goals in the top tier with more than half of the league season still to be played.
Guardiola's charges to get amongst the goals
Guardiola's team can be backed at 43/100 (1.43) with Betsafe to score at least three goals in this game, while the 117/100 (2.17) quote on offer from the same firm for City to hit at least four goals against the Cherries is certainly tempting.
Bournemouth may take a crumb of comfort from City's defensive record, for the hosts have conceded in five of their last six matches in the Premier League; Betsafe go 93/100 (1.93) that there are goals at both ends in this one.
Tips and predictions:
With an average of fewer than one goal per game scored in the Premier League this season, the Cherries could struggle to put the home side under any real pressure and, so, Betsafe's 22/25 (1.88) quote for Manchester City to win to nil may offer best value for punters this weekend.