Despite the visit of fellow top-four contenders Spurs to Old Trafford being just their third league match of the season, Brazil international Fred believes it is already a crucial fixture.
"It's a very important game. This week we've been working, focusing on this game, we want to go out and get the win in front of our home fans," Fred told Sky Sports .
"We know Tottenham are a great team, but we need to get the win if we are to aspire to win the league.
"The Premier League is a great league and there are a lot of great teams and Brighton were better than Man United.
"They got early goals which we didn't manage to achieve. We improved but unfortunately this wasn't enough for a win or a draw.
"Going into the next game, we want to be focused and we want to win, so we can stay in the race for the title."
It has been a rough start to the season for United manager Jose Mourinho, with reports suggesting some players are unhappy working under him.
But Fred insists he is not one of the reportedly disgruntled Red Devils as he is happy at Old Trafford.
"I'm really happy to be working with Jose Mourinho he's a great person and he's always keen to communicate with the squad and help people to be communicative regarding what they're to do on the pitch," he said.
"I'm really happy to be working with him and I hope that I'll be working for him for a while to come."