Jurgen Klopp's side are currently third in the Premier League, six points behind the Red Devils but with a game in hand, and they come into the match against Spurs on the back of a win over Huddersfield Town.
Tottenham also come into the game on a high, having comfortably beaten Man United 2-0 during the week, and they can leapfrog the Reds into third place with a win.
Indeed, Mauricio Pochettino's side arguably boast a psychological edge over their hosts, having thrashed them 4-1 at Wembley back in October.
|Game||Liverpool vs Tottenham Hotspur|
|Date||Sunday, February 4|
|Time||16:30 GMT / 11:30 ET|
|Stream (US only)||fuboTV (7-day free trial)|
TV CHANNEL & LIVE STREAM
In the United States (US), the game can be watched live and on-demand with fuboTV (7-day free trial).
New users can sign up for a free seven-day trial of the live sports streaming service, which can be accessed via iOS, Android, Chromecast, Amazon Fire TV, Roku and Apple TV as well as on a web browser.
|US TV channel||Online stream|
In the United Kingdom (UK), the game can be watched live on TV on Sky Sports Premier League and it can be streamed live online using Sky Go.
|UK TV channel||Online stream|
|Sky Sports Premier League||Sky Go|
SQUADS & TEAM NEWS
|Goalkeepers||Mignolet, Karius, Ward|
|Defenders||Van Dijk, Lovren, Gomez, Moreno, Robertson, Matip, Alexander-Arnold|
|Midfielders||Wijnaldum, Milner, Henderson, Oxlade-Chamberlain, Can, Woodburn, Paulinho|
|Forwards||Firmino, Salah, Mane, Ings, Solanke, Brewster|
Adam Lallana has returned to training but the England international will not be rushed back for the game, while Ragnar Klavan is also unavailable. Nathaniel Clyne is still not ready.
Virgil van Dijk is expected to return to the starting lineup after appearing on the bench against Huddersfield Town.
Potential Liverpool starting XI: Karius; Robertson, Van Dijk, Lovren, Gomez; Wijnaldum, Henderson, Oxlade-Chamberlain; Salah, Mane, Firmino.
|Goalkeepers||Lloris, Vorm, Gazzaniga|
|Defenders||Trippier, Vertonghen, Sanchez, Foyth, Davies, Walker-Peters, Aurier|
|Midfielders||Lamela, Wanyama, Dier, Sissoko, Dembele, Alli, Eriksen, Georgiou, Oakley-Boothe, Winks, Moura|
|Forwards||Son, Kane, Llorente, Sterling|
Lucas Moura could make his debut for the club after signing from Paris Saint-Germain, but the game may come too soon for the midfielder.
Concerns remain over the fitness of Toby Alderweireld and Danny Rose, who are working their way back to full fitness, while Harry Winks is recovering from an ankle injury.
Potential Tottenham starting XI: Lloris; Trippier, Vertonghen, Sanchez, Davies; Dembele, Eriksen, Alli, Dier, Son; Kane.
BETTING & MATCH ODDS
Liverpool are at home and have been installed as favourites by dabblebet, who offer odds of 21/20 on a Reds victory. Spurs are deemed a 5/2 bet to win and a draw is available at 13/5.
Liverpool were totally outclassed by Tottenham when the sides met in the corresponding fixture earlier in the season and they will be determined to avoid a repeat of that at home.
Klopp's men responded to that defeat by going on an 18-game unbeaten run in all competitions, a streak that was only halted towards the end of last month, and they will attempt to summon the same winning mindset at Anfield on Sunday.
Tottenham, on the other hand, followed up that October triumph by losing twice in a row and their form had been patchy for months thereafter. However, they have since stabilised somewhat and have not lost a game since mid December.
Given that the Reds and Spurs are in direct competition for a top-four finish and, with only two points separating them in the league, the importance of this game is magnified considerably so there is sure to be an added layer of tension on Merseyside.