Having been beaten by Croatia in their final group game, the reigning champions have been paired with Italy in a tough last-16 clash.
However, Juanfran insists the focus is solely on the Italians for now – a pragmatic approach that has served Atletico well in the past few seasons.
"Whether our game is the most difficult, we will see," he said. "We can apply the philosophy of Atletico, take it game by game."
The 31-year-old is also adamant that Spain have plenty to be positive about after finishing second in Group D.
"In the majority of the three games, we have been the better team," he added. "I believe that too much has been made about the defeat.
"We are convinced that we are going to qualify for the next round. Any opponent that we get in the last 16 will be tough to play."