Die Mannschaft are without a win in five games, having fallen to a shock 2-1 defeat against Austria last weekend.
However, having recorded a memorable 8-0 victory when the sides last met at the 2002 World Cup, they are 1/25 (1.04) favourites with SportPesa to return to winning ways in this clash.
Four of the hosts' last six friendly matches have resulted in draws, and there are odds of 11/1 (12.00) available on them being held to an embarrassing stalemate here.
Bernd Leno, Jonathan Tah, Leroy Sane and Nils Petersen were the unfortunate provisional squad members to miss out on a place in Joachim Low's final selection.
Jerome Boateng may be rested as he recovers from injury, while Toni Kroos should start after arriving late following the Champions League final.
The Green Falcons have shuffled their pack for the two previous friendlies against Italy and Peru, although are likely to play their strongest line-up as they prepare to take on Russia in the World Cup's opening clash.
While a five-game winless streak that included difficult matches against England, France, Spain and Brazil may have taken the sheen off of Low's team, they will still travel to Russia as one of the favourites to lift the trophy.
Sane's omission from the final squad has merely underlined their quality, while a return of 43 goals in their 10 World Cup qualifiers suggests there is ample firepower even without the Manchester City star.
With Germany keen to sign off with a big win in front of their own fans, odds of 21/20 (2.05) are well worth backing on them scoring at least four goals against an outclassed Saudi Arabia.