Fernando Torres will captain Atletico Madrid on his final appearance for the club.
Torres has yet to confirm his next move but has been linked with a switch to the Chinese Super League or MLS for the latter years of his career, while a reunion with former boss Rafael Benitez at Newcastle United has also been mooted.
With Torres starting in attack alongside fellow former Chelsea forward Diego Costa, Europa League hero Antoine Griezmann has a place on the bench.
Atletico will wear shirts featuring a special patch to mark Torres' last game for the club.
Torres came through the ranks at Atletico, making his first-team debut at the tender age of 17 back in 2001 during the season the club spent in the second division.