One man who will be on the spotlight for this game will be Roma forward Edin Dzeko who will be their biggest threat when they take on FC Porto in the Round of 16.
The Bosnian has made four appearances for the Italian side in the competition and has scored a whopping five goals.
He has a shot rate of 3.8 every game and has two assists to boost, underlining how important he has been for the team.
His inspirational displays, leading the attack, will be very much the cornerstone of Roma's European hopes.
Watch all his best plays in Europe so far here.