The Blues cruised to a 3-0 victory in last week's first leg in west London and will therefore feel confident of completing the job in the Ukrainian capital.
SportPesa make the Blues their 6/5 (2.20) favourites to secure their place in the last eight of the competition with victory in Kiev.
Pedro, Willian and Callum Hudson-Odoi were all on the scoresheet at Stamford Bridge last week and will be hopeful of a starting berth in Kiev. Eden Hazard and Gonzalo Higuain could well be afforded a breather, with the tie seemingly won.
The case for goals
Chelsea have kept just one clean sheet in their last 12 matches away from home and that defensive frailty could offer the most slender of hope to the hosts ahead of this tie. SportPesa go 20/23 (1.87) that there are goals at both ends in Kiev.
The odds compilers offer 9/4 (3.25) Alyaksandr Khatskevich's men score more than one goal in the Ukrainian capital; the Blues have shipped no fewer than 14 goals in their last five away matches.
There have been at least three goals scored in five of Chelsea's last seven matches away from home in this competition and SportPesa offer 11/10 (2.10) that there are more than two goals in this game.
Sarri's side have won eight of their nine Europa League matches so far this season and the Blues will be keen to rubber-stamp their authority on this tie with a fast start on Thursday.
SportPesa go 39/20 (2.95) that Chelsea lead at both half-time and full-time. That particular play would have landed in three of the Blues' last four wins in this competition.
SportPesa, though, offer 20/21 (1.95) that most of the scoring comes in the second half, a selection that would have landed in each of Chelsea's last three matches in this competition.
Furthermore, both goals in the Blues' 1-1 draw with Wolves at the weekend came in the second half. The 20/21 (1.95) quote, then, for most of the goals in Kiev to come after the break could offer outstanding value here.