Juventus manager Massimiliano Allegri urged Paulo Dybala to provide more end product as the attacker prepares for his first start in three competitive matches.
The 24-year-old has netted 12 times in Serie A this season - already one more than he managed last term - although he has only scored once in his last 10 competitive appearances.
He will be joined in the squad for Tuesday's last-16 encounter by returning pair Giorgio Chiellini and Stephan Lichtsteiner, while Gianluigi Buffon, Mario Mandzukic and Juan Cuadrado are all sidelined.
"Dybala is a player capable of 15 to 20 goals in the league. When he gets 20 then he will have done a lot," Allegri said at his pre-match news conference.
"And his characteristics go beyond that. Dybala is a player who must provide assists and score goals because he is not just a poacher.
"Like the others, Paulo is an intelligent player who knows that tomorrow is an important game for him and for Juventus.
"We have had a different system of play in the last few games and I pulled him out, it is very simple. When Paulo plays, we need to exploit the characteristics he has."
The #TIMCup journey begins tomorrow for the Bianconeri. @OfficialAllegri gives his thoughts on #JuveGenoa https://t.co/D1rash3rJU#ForzaJuve pic.twitter.com/gaon8r32Jy — JuventusFC (@juventusfcen) December 19, 2017
Allegri said he would need to decide whether to play Dybala as a single centre-forward or partner him with Gonzalo Higuain.
Marko Pjaca is also an option having sufficiently recovered from a long-term knee injury to sit on the bench in the weekend win over Bologna.