The visitors made two changes in the team that started against Dwarfs in mid-week as defender Awudu Nafiu replaced Emmanuel Owusu while Frank Sarfo Gyamfi returned after few games on the sideline, while Dreams kept faith in goalkeeper Isaac Amoako, handing him the opportunity to face his former side, as Zuberu Sharani led the attack.
The hosts appeared to be in the ascendancy early on and almost took the lead by the fourth minute but Awudu Nafiu made a timely clearance to prevent Zuberu from connecting a pass from Zakaria.
Six minutes later, goalkeeper Felix Annan made a timely save, punching Zuberu's effort for a corner-kick that was wasted.
Kotoko had their first opportunity by the 12th minute following a quick counterattack. Goalkeeper Annan released Obed Owusu with a long ball, with the striker setting up Frederick Boateng, who failed to beat onrushing goalkeeper Amoako.
By the 25th minute, Patrick Arthur made a goal line clearance to prevent the visitors from drawing the first blood. Boateng nearly benefited from a poor clearance after a teeing cross from Emmanuel Gyamfi but the threat was cleared by the defender.
Dreams' early control of the game in the second-half was hindered by a lack of precision in the final third of Kotoko. The returnees continued to waste several opportunities.
By the 58th minute, Kotoko made two quick substitutions as midfielder Jordan Opoku and striker Mawuli Osei came on for Prince Acquah and Emmanuel Gyamfi respectively as they switched to 4-3-3 formation.
Dreams also made changes as George Dwubeng and Richard Addae came on for Arthur and Asamoah respectively.
On the 77the minute, Dreams saw their penalty shout ignored by the referee after Addai fell in the box following a challenge.
Dreams eventually broke the deadlock by the 88th minute through Dwubeng. The youngster kept his cool in the box and slotted home a pass from Zuberu to score the club's first-ever goal against Kotoko in the topflight.
Kotoko pushed men forward in search of an equaliser that never surfaced.
Dreams have moved three places up on the log to fifth position with 11 points, while the Kumasi giants have dropped four places to seventh with 10 points.