Rudiger makes his first start since he played in the 1-0 defeat against Manchester City in September. Cesar Azpilicueta moved to right wing back that day and he will play in that position again on Saturday.
David Luiz and Tiemoue Bakayoko passed late fitness tests to make the game despite picking up knocks against Watford. Chelsea will continue to line up in a 3-4-3 formation despite Conte admitting that the team has struggled for balance since N'Golo Kante sustained a hamstring injury.
Thibaut Courtois makes his 100th appearance in the Premier League, while Pedro makes his first start for Chelsea since his side ran out 4-0 winners over Stoke City.
In fact it is the first time Eden Hazard, Alvaro Morata and Pedro have started together for Chelsea. Ethan Ampadu will become Chelsea's youngest player to play in the Premier League if he comes off the bench.
Chelsea starting XI: Courtois; Rudiger, David Luiz, Cahill; Azpilicueta, Bakayoko, Fabregas, Alonso; Pedro, Morata, Hazard.
Subs: Caballero, Christensen, Ampadu, Zappacosta, Musonda, Willian, Batshuayi.