SportPesa make the home side just 3/8 (1.38) to win the game but better value may lie in the scorer markets given the 2-2 the last time these teams met.
Harry Kane was on target in the reverse fixture as well as as the weekend win against Wolverhampton Wanderers.
The England international has looked a little jaded at times this season following a hectic summer, but the 25-year-old appears to be getting back up to full speed.
Kane is usually just 1/2 (1.50) to find the net but SportPesa have a new customer offer available for this game. Anyone opening an account can back the Spurs striker at a massive 10/1 (11.0). £5 max bet. Winnings paid in bonuses. Terms and conditions apply.
To take advantage of this huge enhanced price simply register using the links provided. Place your first cash bet of £5 on Kane to score at the usual price and if he finds the net then the returns will be topped up to the value of a 10/1 (11.0) winner.
The fact that Mauricio Pochettino's men are in such a poor position should mean the hosts take no chances after letting a 2-1 lead slip in the last fixture between these sides.
What's more, Kane has the best goals per game ratio of any player in Champions League history who has played at least 10 matches. His 11 goals in 13 games includes a strike against Barcelona earlier this season and the England captain should be primed for another big display at Wembley.
Given the usual short price available on Kane scoring this bet should appeal to plenty of punters who can take advantage of the 10/1 (11.0) as new SportsPesa customers.