Diego Simeone's men are well-fancied to push for the title this term and if they are to do so, they will need to win at places like the Estadio Balaidos where they take on Celta Vigo on Saturday.
Celta are unbeaten in their 12 home La Liga matches this calendar year, during which time the likes of Real Madrid, Barcelona, Valencia and Sevilla have all failed to win in Vigo, and bet365 price a home win at 19/4 (5.75).
Atletico, however, boast a strong away record in Galicia and have won this fixture in six of the last seven seasons, so it is little surprise they are priced at 13/20 (1.65) to pick up three more points.
Seven of Celta's 12 home league matches this year have ended as draws and another stalemate is priced at 5/2 (3.50).
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Atletico Madrid will be missing right-back Juanfran who is out with a thigh injury, who is likely to be replaced by Colombian international Santiago Arias.
Celta are waiting on the fitness of defender David Junca, with the summer signing unable to make his debut yet due to a muscle strain.
Last season Atleti conceded just 14 goals in 19 league matches on the road, and we can expect Los Rojiblancos to be a resilient unit defensively again this term.
Even when their opponents manage to engineer a goalscoring opportunity, the brilliance of Oblak often denies them and Atletico are likely to be the toughest team to score against in the Primera Division once more.
Simeone's men kept ten clean sheets on the road last season, including in Vigo, and backing them to record a shutout away from home is often a good angle.
Tips and predictions
Atleti have kept a clean sheet in six of their last eight matches against Celta in all competitions and they are priced at 11/10 (2.10) to keep a clean sheet on Saturday.
The capital side can be backed at 13/8 (2.62) to be the only team to score, while under 2.5 goals in the game is priced at 7/10 (1.70).
Prices correct at the time of writing. Please gamble responsibly.