Burnley have been victorious on seven of the eight occasions Turf Moor has hosted competitive European football and the East Lancashire outfit are 7/5 (2.4) to record a victory inside 90 minutes.
The visitors, who haven’t failed to win a Europa League qualifying match since 2010, are 7/4 (2.75) to uphold that record.
A draw would see Thrylos comfortably progress and can be backed at 11/5 (3.2).
For Burnley, Johann Berg Gudmundsson is sidelined with a muscle injury, whilst new centre-back Ben Gibson was sent off in the first leg and so is suspended. Nick Pope and Steven Defour are long-term absentees.
Olympiakos, meanwhile, could make one or two changes from the side that beat Levadiakos 1-0 in the Greek Super League.
Centre-back Roderick Miranda could come in but wide man Lazaros Christodoulopoulos will surely keep his place after completing a man-of-the-match performance with a fine free-kick.
Thrylos to break?
Pedro Martins’ troops might no longer have home advantage, but it seems plausible that their opponents’ desperation to bridge the two-goal deficit could disrupt their structure and hand the visitors opportunities to counter-attack.
Olympiakos to win with the -1 handicap at 5/1 (6.0) – which will land if they are victorious in the 90 minutes by a margin of more than one goal – could prove worth a punt.
Preview and predictions
Our best bet though is the 11/4 (3.75) on an Olympiakos win with over 1.5 goals scored, a shot which looks great value considering Burnley have shipped 10 in their last three and will be forced to throw caution to the wind.