The Rams sit one place outside the play-off spots, although a game in hand would allow them to climb back into the top six with a victory over Millwall on Wednesday.
888Sport make Derby 19/20 (1.95) favourites to secure the three points they'd need to climb above Bristol City. Milwall on the other hand are 29/10 (3.90) underdogs with 47/20 (3.35) available on a draw at Pride Park.
The visitors have saved their best performances for the FA Cup this term and have a quarter-final clash against Chris Hughton's Seagulls on the horizon after edging past Wimbledon.
Despite some stuttering form from the Rams, those odds about the visitors don't make much appeal either. The Lions have won only once on the road in the Championship this season and that came at bottom club Ipswich Town.
The best approach here looks to be turning to the goals markets. Neither team boast a prolific attack and so opposing a high-scoring game makes an appealing prospect. Under 2.5 goals is 17/20 (1.85) with 888Sport at the time of writing.
Despite being on the cusp of the play-offs, Frank Lampard's side have only scored 43 goals this term. That is the 12th-best tally in the second tier but it's somewhat counteracted by a backline that has conceded just 36 times so far.
Only one of Derby's last six Championship games has seen three goals scored and Millwall look unlikely to pose too much of a threat to the Rams' backline.
The visitors have averaged under a goal per game on their travels this season and their recent run suggests opposing action in the final third is a solid move.
Neil Harris' side have seen over 2.5 goals land in just one of their previous eight league matches and that defensive approach simply adds to the appeal of a low-scoring game in the East Midlands.
With Derby taking a defence first approach and Millwall rarely being involved in goal-fests, under 2.5 goals looks the best bet in this game at 17/20 (1.85) with 888Sport.