Arsenal will start with Mesut Ozil, Alexis Sanchez and Alexandre Lacazette all present in their starting XI to face north London rivals Tottenham.
Gunners boss Arsene Wenger has previously received criticism for leaving £52m record signing Lacazette on the substitutes bench for games against Liverpool and Manchester City, but has opted to start the trio for the second time in the league.
Shkodran Mustafi returns to the line-up following his injury while Aaron Ramsey partners Granit Xhaka in central midfield.
Tottenham manager Mauricio Pochettino has an almost fully fit squad to choose from and fields an exciting front three of Christian Eriksen, Dele Alli and Harry Kane, although in defence Belgium international Toby Alderweireld misses out through injury.
Davison Sanchez starts in a back four with Kieran Trippier, Eric Dier and Jan Vertoghen while Ben Davies and Moussa Dembele also feature in the Spurs starting Xi.
Arsenal starting XI: Cech; Koscielny, Mustafi, Monreal; Bellerin, Ramsey, Xhaka, Kolasinac; Ozil, Lacazette, Alexis
Tottenham starting XI: Lloris; Trippier, Dier, Sanchez, Vertonghen; Davies, Dembele; Sissoko, Eriksen, Dele; Kane