After a positive start to life under new manager Unai Emery, the Gunners' 22-game unbeaten run came to an end when they fell to a 3-2 defeat against Southampton last Sunday.
Emery's side are currently fifth in the table, three points behind fourth-placed Chelsea, and know a win on Saturday is vital if they're to carry on competing for a place in the Champions League positions.
Burnley find themseleves in the relegation zone heading into this match, having collected just 12 points from their opening 17 league fixtures.
Sean Dyche will, however, have taken heart from an improved performance in their 1-0 defeat to Spurs last weekend, with Mauricio Pochettino's side snatching a last minute winner through Christian Eriksen.
|Game||Arsenal vs Burnley|
|Date||Saturday, December 22|
|Time||12:30pm GMT / 7:30am ET|
|Stream (US)||fubo TV (7-day free trial)|
TV Channel, Live Stream & How To Watch
In the United States (US), the game can be watched live and on-demand with fuboTV (7-day free trial) .
New users can sign up for a free seven-day trial of the live sports streaming service, which can be accessed via iOS, Android, Chromecast, Amazon Fire TV, Roku and Apple TV as well as on a web browser.
|US TV channel||Online stream|
|NBCSN||fubo TV (7-day free trial)|
In the United Kingdom (UK), the game can be watched live on Sky Sports Main Event/Sky Sports Premier League and streamed on Sky Go.
|UK TV channel||Online stream|
|Sky Sports Main Event/Sky Sports Premier League||Sky Go|
Squads & Team News
|Goalkeepers||Leno, Cech, Martinez|
|Defenders||Lichtsteiner, Koscielny, Monreal, Sokratis, Maitland-Niles, Jenkinson|
|Midfielders||Xhaka, Torreira, Guendouzi, Elneny, Ramsey, Mkhitaryan, Ozil, Iwobi, Smith Rowe|
|Forwards||Aubameyang, Lacazette, Nketiah|
Arsenal defender Shkodran Mustafi is still out with a hamstring injury but Sead Kolasinac is fit, meaning Nacho Monreal moves inside to centre-back.
Hector Bellerin remians absent, but Sokratis Papastathopoulos is available again after suspension.
Mesut Ozil returns to the starting XI after being dropped from the squad against Tottenham while Mohamed Elneny makes a rare start, with Lucas Torreira on the bench.
Arsenal starting XI: Leno; Maitland-Niles, Sokratis, Monreal, Kolasinac; Guendouzi, Elneny, Xhaka; Ozil; Aubameyang, Lacazette.
|Goalkeepers||Hart, Heaton, Pope, Lindegaard|
|Defenders||Lowton, Tarkowski, Mee, Gibson, Bardsley, Long, Taylor|
|Midfielders||Cork, Brady, Gudmundsson, Hendrick, Westwood, McNeil|
|Forwards||Vokes, Barnes, Wood, Vydra, Agyei|
Clarets winger Aaron Lennon has had surgery on a torn cartilage in his knee and will be out for the forseeable future.
Midfielder Johann Berg Gudmundsson returned to training earlier this week but is not involved while Steven Defour remains out.
Sean Dyche experimented a three-man defence against Spurs and deploys it again at the Emirates on Saturday.
Burnley starting XI: Hart; Long, Tarkowski, Mee; Bardsley, Westwood, Cork, Hendrick Taylor; Wood, Barnes.
Betting & Match Odds
Arsenal are priced at odds of winning 1/4 according to bet 365 , while a draw is available at 11/2. A win for Burnley is priced at 14/1.
Much has been made of Emery's decision to overlook Ozil in recent weeks, with the German not even making the bench for Wednesday's clash with Spurs.
The Arsenal boss was pressed on his thinking behind the midfielder's omission and remained coy, insisting it was simply 'a tactical decision'.
But despite reports suggesting that the German could be on the move in January, Emery confirmed that Ozil will be back in the squad to take on Burnley.
"Every player wants to play and be okay to help the team when we need," said the Spaniard.
"The frustration is the same for everybody when they didn’t play in a match.
"But I spoke with him and with the regularity in the season, I am telling him what we need from him and he has the commitment to help us and the quality and the characteristics to help us when the team needs his moments in the pitch in one game.
"Tomorrow he is in the 18 players, in the squad."
Burnley manager Dyche says he was happy with the way his side dealt with a change of system to a back three last weekend and strongly hinted that he could stick with the system in the coming weeks.
"I played in it myself and I know how the system works, I think the timing, the use of the right players at the right time, and loads of different things go into the thinking," said Dyche.
"It has to suit the players first, and when I looked at the group we're moulding, and they way they were operating, I thought it was a good time to try it."