The Gunners saw their 22-match unbeaten run ended when they suffered a 3-2 defeat against Southampton at St Mary's last Sunday before crashing out of the League Cup at the hands of arch-rivals, Tottenham, on Wednesday night.
Burnley find themselves in the bottom three and Sean Dyche's team will be desperate to heap yet more misery on the Gunners when they visit north London.
Since being beaten by Manchester City on the opening weekend of the season, Arsenal have gone eight Premier League home matches without defeat and are SportPesa's overwhelming 4/17 (1.24) favourites to beat Burnley.
The Clarets have collected just one point from their last five Premier League matches away from home. SportPesa offer 13/1 (14.0) that Burnley claim a vital victory here.
The same firm go 21/4 (6.25) that the visitors pick up a precious point in their battle to beat the drop.
Shkodran Mustafi, Konstantinos Mavropanos, Rob Holding and Hector Bellerin are all out, leaving the Gunners short of defensive resources.
Dyche has a fully fit squad at his disposal following Nick Pope's return to action for the under-23s at the beginning of the week.
Goals for the Gunners?
Only Manchester City have scored more often in the Premier League than Arsenal thus far this term. SportPesa go 20/21 (1.95) that Emery's men grab more than two goals here. The same firm go 33/20 (2.65) that the Gunners (-2) beat the handicap mark.
Remarkably, Arsenal have never led at half time in the Premier League thus far this term. The hosts, however, will fancy their chances of putting that particular statistic to bed this weekend.
Burnley have drawn a blank in four of their last five fixtures on the road and the shot-shy Clarets could struggle to make much of an impact here.
As such, SportPesa's 7/5 (2.40) quote for Arsenal to win both halves could represent real value ahead of this match.