The Gunners were comfortably beaten when the sides met at Wembley in Sunday’s Carabao Cup final, losing out by an emphatic 3-0 scoreline.
However, having lost just one of their last 20 home matches in the league, they are available at 10/3 (4.33) with dabblebet to bounce back in style by coming out on top here.
Pep Guardiola’s men ran out 3-1 winners in November’s reverse fixture at the Etihad Stadium, and can be backed at 3/4 (1.75) to make it three wins over Arsenal this season.
Three of the last four encounters between the sides at this ground have resulted in draws, and you can get odds of 3/1 (4.00) on them cancelling each other out once again.
Nacho Monreal went off injured at Wembley and is unlikely to feature, although Henrikh Mkhitaryan is available after being cup tied for the final and Petr Cech is set to return in goal.
Fernandinho is also a doubt for the Citizens after suffering a hamstring injury on Wednesday, while Raheem Sterling is also struggling.
However, Fabian Delph will return from suspension and Gabriel Jesus is fit again after two months out.
Unbeaten in four league home games against this opposition, Arsene Wenger’s men may be optimistic of atoning for Sunday’s disappointment with victory here.
However, such was the gap in quality between the two sides at Wembley, it would take an almighty turnaround for them to take anything from this game.
Considering Arsenal have won just five of their last 15 fixtures and lost four of the most recent six, odds of 3/4 (1.75) actually seem like solid value.
City have won 29 and lost only one of their previous 35 league matches and will fancy themselves to come out on top once again.