Having failed to win any of the last six encounters with this opposition, they are priced at 23/10 (3.30) with William Hill to underline just how far they have come with a first victory since 2015.
However, the Reds are joint top of the league and unbeaten in 11 league fixtures, making them 21/20 (2.05) favourites to come out on top in North London.
Two of the last three encounters between the pair at this ground have resulted in draws, and you can get odds of 14/5 (3.80) on them sharing the spoils once again here.
Hector Bellerin, Nacho Monreal, and Sead Kolasinac will face late fitness tests ahead of the match, while Mohamed Elneny, Konstantinos Mavropanos and Laurent Koscielny all remain sidelined.
Jordan Henderson and Naby Keita will both be pushing for a place in the visiting squad as they both continue their recovery from hamstring injuries.
Meetings between these sides are usually one of the highlights of the Premier League season, with their last eight matches producing 42 goals – an average of over five per game.
More entertainment looks likely considering only Manchester City have scored more goals than the Gunners so far this campaign, while they have kept only two clean sheets in their 10 league matches.
With Jurgen Klopp’s men showing signs of their attacking best after scoring four times in each of the last two fixtures, odds of 11/10 (2.10) offer solid value on them ensuring over 3.5 goals are scored for their ninth league meeting in 10 with Arsenal.