Arsenal are 17 games unbeaten in all competitions and head coach Unai Emery faces his first north London derby on Sunday with just three points between the two arch rivals.
The Gunners have looked reinvigorated under Emery this season but it's worth noting they have have won just one of their last eight matches against Spurs.
Emery's side have conceded first in their last three Premier League games but have looked sublime up front with fans recently chanting 'we've got our Arsenal back'.
Danny Welbeck is ruled out with a suspected broken ankle following his shocking injury against Sporting CP, while Nacho Monreal is sidelined with a hamstring injury.
Dinos Mavropanos faces further time out on the sidelines with a groin injury until December, with Laurent Koscielny back in contention after his long-term achilles issue.
Arsenal have no suspended players for this match.
Possible Arsenal Starting Line-Up
Emery is expected to stick with Sead Kolasinac at left-back following Monreal's injury, with Alexandre Lacazette and Pierre-Emerick Aubameyang both likely to return to the starting line-up.
Henrikh Mkhitaryan could start after not playing against Vorskla while Alex Iwobi is also an option as he didn't travel with the squad to Ukraine.
Granit Xhaka and Lucas Torreira are expected to anchor the midfield, but Emery faces a dilemma over which centre-backs to pick with Sokratis, Rob Holding and Shkodran Mustafi all available.
Danny Rose is back in the fold while Jan Vertonghen returned to first team action against Inter Milan after six weeks on the sidelines.
Kieran Trippier could be involved but Mousa Dembele, Davinson Sanchez and Victor Wanyama are all out with long-term injuries.
Pochettino's side are three points above their north London rivals in third place.
TV Coverage & Kick-Off Time
Kick-off is 2:05pm GMT (9:05am ET) on Sunday, and the game will be broadcast live on Sky Sports in the United Kingdom. It will be shown on NBCSN in the United States, and on various channels around the world.
Best Opta Match Facts
Arsenal have won one of their last eight Premier League matches against Spurs (D4 L3), though that win came at the Emirates in this fixture last season.
Spurs have won just one of their last 25 away Premier League games against Arsenal (D10 L14), a 3-2 victory in November 2010.
Premier League matches between Arsenal and Tottenham have seen both teams find the net more often than any other fixture in the competition (34).
Arsenal’s Unai Emery and Tottenham boss Mauricio Pochettino haven’t faced since April 2012, when Pochettino’s Espanyol side won 4-0 against Valencia in La Liga. However, Emery won all three of his home La Liga meetings with Pochettino between January 2010 and December 2011.
Arsenal’s Pierre-Emerick Aubameyang has scored with his last eight shots on target in the Premier League – the last keeper to save one from him was West Ham’s Lukasz Fabianski in August.